Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Iodotrimethylsilane-Promoted Conjugate Addition of Organocopper Reagents, DDQ oxidation of Arylpropenes and Synthesis of 2-Arylcoumarans

    Författare :Tommy Iliefski; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2; DDQ; arylcoumaran; cinnamaldehyde; 6-dicyanobenzoquinone; iodotrimethylsilane; copper acetylides; 1; 3-dichloro-5; neolignan; 4-addition; arylpropene; TMSI; organocopper; conjugate addition;

    Sammanfattning : This thesis is divided into three parts: conjugate additions of organocopper reagents, DDQ oxidations of arylpropenes, and synthesis and steric assignment of 2-arylcoumarans. The iodotrimethylsilane(TMSI)-promoted conjugate addition of alkylcopper and copper acetylides to certain a,b-unsaturated carbonyl compounds is investigated. LÄS MER

  3. 2. Bisindoles : synthesis and reactions

    Författare :Eva Koch; KTH; []
    Nyckelord :;

    Sammanfattning : In this thesis, synthesis of various bisindoles have beendeveloped.2,3-Bis-(3-indolyl) succinic acid derivatives wereobtained via iodine promoted coupling of the trianion ofindole-3-acetic acid (IAA) or from the dianion of themethylester of IAA. These compounds were converted to2,3-bis(3-indolyl) maleimides (arcyriarubin analogues) by DDQoxidation. LÄS MER

  4. 3. Strategies and Methods for Synthesizing Scytonemin Analogues

    Författare :Andreas Ekebergh; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Natural product synthesis is an exciting field of organic chemistry, directed toward constructing naturally occurring compounds, which often are both chemically complex and biologically intriguing. Scytonemin is a unique, dimeric natural product found in cyanobacteria. LÄS MER

  5. 4. Synthetic studies of marine indole alkaloids and related systems

    Författare :Ann-Louise Jonsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Marine indole alkaloids; antifouling; synthesis; diketopiperazines; HWE-reaction; bis indole alkaloids; imidates; carbazole alkaloids;

    Sammanfattning : This thesis is mainly focussed oil the synthesis of marine indole alkaloids and related systems, many of which display interesting biological activities. In the first part of this thesis we could establish and confirm the stucture of barettin and 8,9dihydrobarettin, isolated from the marine sponge Geodia baretti. LÄS MER

  7. 5. Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives

    Författare :Azadeh Nakhai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pyrazole; indazole; tetrahydroindazoles; hexahydroindazoles; alpha; beta-unsaturated ketones; dihydropyrazolone; 3; 3 -biindolyl; 3; 3 -biindazolyl; o-azidobenzonitriles; benzotriazine; aryl-triazene;

    Sammanfattning : This thesis will mainly focus on the chemistry of nitrogen containing heterocyclic compounds, particularly pyrazole and benzotriazine and related ring systems to these compounds. The first part includes a short introduction to biologically important compounds as well as a description of reactivity and chemistry of benzo[c]pyrazole (indazole) and its derivatives. LÄS MER