Sökning: "Crohn s disease"

Visar resultat 6 - 10 av 22 avhandlingar innehållade orden Crohn s disease.

  1. 6. Genetic Studies of Psoriasis and Psoriatic Arthritis

    Författare :Camilla Friberg; Göteborgs universitet; []
    Nyckelord :psoriasis; psoriatic arthritis; complex disease; autoimmune disease; linkage analysis; association analysis; PSOR5; 3q21; 5q31-32; SLC22A4; SLC22A5; CSTA; ZNF148; expression;

    Sammanfattning : Psoriasis and psoriatic arthritis are common chronic immune-mediated diseases of the skin and joints. Psoriasis affects approximately 2-3 % of the Caucasian population and about 30 % of all psoriasis patients develop psoriatic arthritis. LÄS MER

  3. 7. Surgery and recurrence in Crohn’s disease

    Författare :Olle Bernell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Previous studies on risk factors for resection and postoperative recurrence in Crohn's disease (CD) have given inconclusive results. The aim of this study is to assess the probability of resection and recurrence in the treatment of CD and to define factors affecting the course of the disease. LÄS MER

  4. 8. Surgery and stomas in Crohn's disease

    Författare :Thordis Disa Kalman; Pär Myrelid; Johan D Söderholm; Bjørn Moum; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This study investigates the evolution of abdominal surgery in treatment of Crohn´s disease (CD) in the era of immunomodulatory drugs and biologicals. It concerns risk of abdominal surgery overall and sub-categories of abdominal surgery, risk of repeat surgery and factors that affect this risk, and risk of getting a stoma. LÄS MER

  5. 9. Immunopathogenesis of Gai2-deficient mice. A model of inflammatory bowel disease

    Författare :Lena Öhman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory Bowel Disease; Mucosa; Apoptosis; Bordetella pertussis; G-protein;

    Sammanfattning : The intestinal mucosa is the largest lymphoid organ in the body, and it simultaneously has to protect us from any pathogen that might enter the gastrointestinal tract as well as maintaining tolerance to most antigens, mainly in the form of dietary constituents and microbial products. A dysfunctional control of local intestinal immune responses may lead to development of Inflammatory Bowel Disease (IBD) - the common name for ulcerative colitis (UC) and Crohn´s disease (CD). LÄS MER

  7. 10. Interindividual differences in thiopurine metabolism : studies with focus on inflammatory bowel disease

    Författare :Sofie Haglund; Sven Almer; Jan Söderman; Curt Peterson; Åke Nilsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The thiopurines, 6-mercaptopurine and its prodrug azathioprine, are used in the treatment of inflammatory bowel disease, ulcerative colitis and Crohn´s disease. The main active metabolites are the phosphorylated thioguanine nucleotides (6-TGNs) and methylated thioinosine monophosphate (meTIMP). LÄS MER