Sökning: "Cardiac progenitor cells"
Visar resultat 11 - 15 av 18 avhandlingar innehållade orden Cardiac progenitor cells.
11. Focus on fibroblasts : development, plasticity, and therapeutic challenges in the cardiac fibroblast lineage
Sammanfattning : Cardiac fibroblasts (CFs) are cells of mesenchymal origin and represent a heterogeneous population in the mammalian heart. They secrete extracellular matrix (ECM) molecules providing structural support during heart development and homeostasis. In response to injury, CFs are activated and undergo phenotypic conversion to myofibroblasts (myoFBs). LÄS MER
12. Single-cell analysis of mammalian cardiogenesis elucidating an essential role of outflow tract progenitors
Sammanfattning : The heart is the first organ to form and start to function during mammalian embryogenesis. This complex organ system is constructed by a diverse set of cell types, involving mesodermal precursors and heart progenitors, at the earliest embryonic stages. LÄS MER
13. Fate selection in the neural crest lineage and its regulation
Sammanfattning : The neural crest is a transient embryonic progenitor cell population that generates a diverse array of cell and tissue types, including cartilage, bone, teeth, soft connective and adipose tissues, peripheral sensory and autonomic neurons, myelinating and non-myelinating Schwann cells, melanocytes, cardiac outflow tract, adrenal medulla and other derivatives. Neural crest cells start as neuroepithelial cells forming at the border of neural and non-neural ectoderm in a vertebrate embryo. LÄS MER
14. A genome-wide screen for essential genes that controls the formation of human heart progenitors
Sammanfattning : The heart is a complex organ system composed of multiple types of tissues. These tissues are produced by a diverse set of muscle and non-muscle cells, originated from a few pools of progenitors. LÄS MER
15. Novel technologies for studies of structural and functional connections
Sammanfattning : To understand the mechanisms underlying the correct functioning of an organ it is important to study its architecture and how the interactions between cells are leading to a specific function. Specifically, the connections that form in the brain are related to the pattern of activation that neurons have, and can help to understand what is the function of each region. LÄS MER
