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1. 1. Design and application of RNA therapeutics for splice site mutations

   Författare :Burcu Bestas; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Precursor messenger RNA splicing is one of the most fundamental and complex mechanisms in eukaryotes. Over 90% of the human genes undergo alternative splicing, which is essential for the regulation of gene expression. A dynamic RNA-protein complex called the spliceosome catalyzes splicing. LÄS MER