Sökning: "Bcl-xL"

Visar resultat 6 - 10 av 23 avhandlingar innehållade ordet Bcl-xL.

  1. 6. Vascular development and safeguard mechanisms against tumorigenesis : oncogene-induced apoptosis and cellular senescence

    Författare :Eduar Hejll; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis;

    Sammanfattning : Angiogenesis, apoptosis and senescence are all cellular processes that have an impact on tumor development. Angiogenesis or the new vessel formation from pre-existing ones is known to be required for invasive tumor growth and metastasis. LÄS MER

  3. 7. Predictive markers : for treatment sensitivity in head and neck squamous cell carcinoma

    Författare :Lovisa Farnebo; Karin Roberg; Ann-Charlotte Johansson; Lena Norberg-Spaak; Antti Mäkitie; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Head and neck cancer is the sixth most common cancer world wide. In Sweden approximately 850 new cases are diagnosed each year, and two thirds are men. The past decades of improved treatment strategies have unfortunately not significantly improved the five-year survival rates for this group of patients. LÄS MER

  4. 8. In vitro studies on anti-leukemic effects of tetracycline's analogues and cyclophosphamide

    Författare :Mona Fares; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Leukemia is a heterogeneous group of hematological malignancies that originate from the bone marrow. Leukemias are classified as acute or chronic. Although acute leukemia affects patients of all ages, acute lymphoid leukemia is predominant in children and young adults while acute myeloid leukemia (AML) is predominant in the elderly. LÄS MER

  5. 9. Neuroendocrine tumors of the digestive system : Modulation of apoptosis and factors associated with growth regulation during biotherapies

    Författare :S. A. Hassan Imam; Uppsala universitet; []
    Nyckelord :Medical sciences; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Neuroendocrine tumors of the gut have the potential to create life-threatening syndromes which become difficult to treat. Tumor mass reduction, by medical therapy, is one of the choices of treatments. LÄS MER

  7. 10. Regulation of Apoptosis in Hematopoietic Progenitor Cells: Involvement of Different Signaling Pathways

    Författare :Maria Kraft; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokines; apoptosis; cell cycle; c-Kit; Flt3; Flt3-ITD; Akt; Bcl-2; FoxO3; mouse; hematopoiesis; progenitor;

    Sammanfattning : Proliferation, differentiation, and survival of hematopoietic stem cells and multipotent progenitor cells are regulated by cytokines and cell-cell interactions. Kit ligand (KL) and Flt3 ligand (FL) have pleiotropic effects, promotes survival, but are nonredundant. LÄS MER