Sökning: "Atorvastatin"

Visar resultat 6 - 10 av 18 avhandlingar innehållade ordet Atorvastatin.

  1. 6. Targeting the role of statins in breast cancer – through translationally edged clinical trials

    Författare :Maria Feldt; Bröstcancer - prevention & intervention; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : AbstractBreast cancer incidence is increasing, and despite major progress in the treatment, breast cancer is still the leading cause of death from cancer among women. Thus, there is a constant need for new treatment options. LÄS MER

  3. 7. Hemostasis and microvascular function in type 1 diabetes : effects of treatment with statin and aspirin

    Författare :Sara Tehrani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Patients with type 1 diabetes often develop microvascular complications and are at increased risk of premature cardiovascular disease. Women with type 1 diabetes lack the normal female protection against cardiovascular disease and may even be at higher risk compared with men with type 1 diabetes. LÄS MER

  4. 8. On the regulation and effects of chronic inflammation in inflammatory bowel disease

    Författare :Olof Grip; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterologi; statins; monocytes; eosinophils; dysplasia; thrombosis; ulcerative colitis; Crohn s disease; inflammation; inflammatory bowel disease; Gastro-enterology;

    Sammanfattning : Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. LÄS MER

  5. 9. Cell derived microparticles : method development, and clinical and experimental studies

    Författare :Fariborz Mobarrez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cell derived microparticles (MP) are released from the cell membrane upon activation or apoptosis. They resemble their parent cell by exposing similar proteins or surface receptors. This enables identification of their cellular origin. LÄS MER

  7. 10. Statin-induced cellular effects mediated by the P2X7 receptor

    Författare :Oras Mistafa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol-lowering statins have been shown to inhibit growth of different cancer cells both in vitro and in vivo. Epidemiological studies also indicate a chemopreventive effect of statins. We have investigated the effect of statins on Akt/protein kinase B signaling and their sensitizing effect of cytostatic drugs. LÄS MER