Sökning: "Anna Hagenkort"

Hittade 1 avhandling innehållade orden Anna Hagenkort.

1. 1. Exploiting nucleotide metabolism to improve cancer therapy : by targeting dUTPase, dCTPase and NUDT15

   Författare :Anna Hagenkort; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Synthetic nucleobase- and nucleoside-analogs have stood the test of time and remain a cornerstone in the treatment regimen against various forms of cancer. Due to their resemblance to endogenous nucleotides these antimetabolites interfere with cellular pathways, including nucleotide metabolism, as well as DNA and RNA synthesis. LÄS MER