Sökning: "Alzheimer disease amyloid apolipoprotein E fibrils ligands liquid chromatography mass spectrometry protease resistance"

Hittade 1 avhandling innehållade orden Alzheimer disease amyloid apolipoprotein E fibrils ligands liquid chromatography mass spectrometry protease resistance.

1. 1. Molecular mechanisms of Ab amyloid deposition in Alzheimer disease

   Författare :Jan Näslund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Alzheimer disease amyloid apolipoprotein E fibrils ligands liquid chromatography mass spectrometry protease resistance;

   Sammanfattning : The general aim of this study was to investigate the mechanisms underlying amyloid b-peptide (Ab) amyloid deposition in Alzheimer disease (AD) brain. Primary structure of intact Ab variants in amyloid partially purified from brains of AD patients and non-demented controls was determined. LÄS MER