Sökning: "1beta-hydroxylated bile acids"

Hittade 1 avhandling innehållade orden 1beta-hydroxylated bile acids.

1. 1. On the role of cytochrome P450 3A4 in the metabolism of cholesterol and bile acids

   Författare :Karl Bodin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Oxysterols; 4beta-hydroxycholesterol; 1beta-hydroxylated bile acids; 22hydroxylated bile acids; 3-oxo bile acids; gas chromatography-mass spectrometry;

   Sammanfattning : The origin of 4beta-hydroxycholesterol, a major oxysterol in human circulation, has previously been unknown. In this thesis, the formation and elimination of this compound are investigated by various techniques. The biological effects of 4beta-hydroxycholesterol are also discussed. LÄS MER