Sökning: "osteopontin"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet osteopontin.

  1. 1. Studies on extracellular matrix proteins in vascular disease

    Detta är en avhandling från Åsa Ström, Section for Connective Tissue Biology, BMC, C12, 221 84 Lund

    Författare :Åsa Ström; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; smooth muscle cells; osteopontin; extracellular matrix; atherosclerosis;

    Sammanfattning : The composition of the vascular extracellular matrix (ECM) is altered during remodeling conditions such as atherosclerosis. The changed ECM regulates events that are important for the progression of disease including smooth muscle cell (SMC) behaviour and collagen fiber formation. LÄS MER

  2. 2. Injury-Induced Signalling in Arterial Smooth Muscle Cells

    Detta är en avhandling från Sara Moses, Lund University, Dept. Cell and Molecular Biology, BMC C12, 221 84 Lund

    Författare :Sara Moses; Lunds universitet.; Lund University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; GAG; Klinisk biologi; proteoglycan; osteopontin; ERK; MAPK; signalling; smooth muscle cell; injury;

    Sammanfattning : The vascular wall is an active, elastic and integrated organ made up of cellular and extracellular matrix (ECM) components. It is not a static organ; the components dynamically change and reorganize in response to physiological and pathological stimuli. Vascular injury induces a complex healing process, analogous to generalised wound healing. LÄS MER

  3. 3. Role of NFAT (nuclear factor of activated T cells) in vascular smooth muscle

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Lisa Nilsson-Berglund; Lunds universitet.; Lund University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proliferation; vascular smooth muscle; A-285222; osteopontin; AIF-1; diabetes; vascular disease; calcium; glucose; NFAT;

    Sammanfattning : The calcium-dependent transcription factor NFAT was first described as a key player in immune cell regulation. Since then, NFAT signaling has been shown to be crucial for normal vascular development during embryogenesis. LÄS MER

  4. 4. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

    Detta är en avhandling från Vascular ET-coupling, Lund University

    Författare :Anna Zetterqvist; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular; NFAT; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

    Sammanfattning : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. LÄS MER

  5. 5. Diabetic Vascular Complications & Inflammation - role of NFAT and TNFalpha

    Detta är en avhandling från Lund University

    Författare :Jenny Nilsson Öhman; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hyperglycemia; vascular; osteopontin; NFAT; diabetes; retinopathy; TNF; UTP;

    Sammanfattning : Vascular complications of diabetes account for the majority of morbidity and mortality among diabetic patients. Large clinical trials have identified hyperglycemia as a risk factor in the development of diabetic vascular complications. LÄS MER