Sökning: "osteopontin"

Visar resultat 21 - 25 av 41 avhandlingar innehållade ordet osteopontin.

  1. 21. On dysregulated inflammation and airway host defense

    Författare :Ravi K. V. Bhongir; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aiway inflammation; Chronic obstructive pulmonary disease COPD ; Cystic Fibrosis; Pseudomonas aeruginosa; DNase I;

    Sammanfattning : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. LÄS MER

  3. 22. Immunopsychiatry from a transdiagnostic perspective : the immunometabolic interplay

    Författare :Ulrika Hylén; Susanne Bejerot; Eva Särndahl; Daniel Eklund; Daniel Lindqvist; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; immunopsychiatry; immunometabolism; transdiagnostic approach;

    Sammanfattning : Background/Objective: Psychiatric disorders are common and they significantly impact quality of life. It has been proposed that inflammatory processescontribute to the emergence of psychiatric disorders. In addition to inflammation, disturbances in metabolic pathways have been seen in individuals with various psychiatric disorders. LÄS MER

  4. 23. Functional aspects of prothrombin in bone

    Författare :Erik Karlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prothrombin (PT) is the inactive zymogen to the serine protease alpha-thrombin which in the coagulation cascade is responsible for clot formation through converting fibrinogen to fibrin. PT has been shown to be present in calcified bone matrix, and alpha-thrombin has been implicated in various bone resorbing disorders of inflammatory origin, such as rheumatoid arthritis and periodontitis. LÄS MER

  5. 24. Isolation and characterization of lipid-associated and neurosecretory polypeptides

    Författare :Margareta Stark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lipid-interacting proteins play important roles in all living organisms. This thesis focuses on isolation and characterization of an enzyme in the triacylglycerol biosynthesis (phosphatidic acid phosphatase, PAP), hydrophobic polypeptides in bile, and polypeptides in cerebrospinal fluid. LÄS MER

  7. 25. Aseptic Loosening of Orthopedic Implants : Osteoclastogenesis Regulation and Potential Therapeutics

    Författare :Mehdi Amirhosseini; Anna Fahlgren; Göran Andersson; Teun J. de Vries; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. LÄS MER