Sökning: "liver transplantation"

Visar resultat 1 - 5 av 131 avhandlingar innehållade orden liver transplantation.

  1. 1. Renal function after transplantation of the liver and intestine

    Författare :Gustaf Herlenius; Göteborgs universitet; []
    Nyckelord :adult liver transplantation; pediatric liver transplantation; intestinal transplantation; multivisceral transplantation; immunosuppression; calcineurin inhibitors; glomerular filtration rate; renal function; nephrotoxicity; chronic kidney disease; renal replacement therapy; mortality;

    Sammanfattning : Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal function and risk factors for developing CKD in adults and children after LT and IT. LÄS MER

  3. 2. Pancreatic Islet Transplantation : Modifications of Islet Properties to Improve Graft Survival

    Författare :Sanja Cabric; Olle Korsgren; Bo Nilsson; Peetra Magnusson; Michael Breimer; Uppsala universitet; []
    Nyckelord :Medicine; Diabetes; islet transplantation; islets of Langerhans; coagulation activation; IBMIR; hirudin; heparin; growth factor; angiogenesis; Medicin;

    Sammanfattning : During the past decade clinical islet transplantation has become a viable strategy for curing type 1 diabetes. The limited supply of organs, together with the requirement for islets from multiple donors to achieve insulin independence, has greatly limited the application of this approach. LÄS MER

  4. 3. Liver transplantation in man. Gastrointestinal perfusion and inflammatory response

    Författare :Ebbe Rønholm; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carbondioxide; complement activation; cytokines; endotoxaemia; hydrogen-ion concentration; liver transplantation; laser-Doppler flowmetry; PMN elastase; regional blood flow; reperfusion;

    Sammanfattning : Patients undergoing liver transplantation develop a systemic inflammatory response which eventually continues with development of a multiple organ dysfunction syndrome (MODS). Gastro-intestinal hypoxia or bacterial translocation has been proposed as the "motor" of MODS. LÄS MER

  5. 4. Renal injury in liver transplantation clinical and mechanistic studies

    Författare :Åsa Norén; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver transplantation; Renal injury; Ischemia reperfusion injury;

    Sammanfattning : ABSTRACT Background: Renal injury in liver transplantation (LT) is common and presents both as early and late insufficiency. These conditions are interconnected and have substantial impact on the long-term outcome. LÄS MER

  7. 5. Immunity to Salmonella infection

    Författare :Cecilia Johansson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; cytokines; antigen presentation; liver; dendritic cells; Salmonella; gram negative bacteria;

    Sammanfattning : The immune system has several strategies to combat infections. The present study investigates various aspects of the interaction between Gram negative bacteria, particularly Salmonella, and antigen presenting cells (APC). Salmonella is an intracellular bacterium infecting mice and man. LÄS MER