Sökning: "optimized sample preparation"
Visar resultat 1 - 5 av 25 avhandlingar innehållade orden optimized sample preparation.
1. Development and Investigations of Novel Sample Preparation Techniques : Electrochemical Extraction and Evaluation of Miniaturized Analytical Devices Coupled to Mass Spectrometry
Sammanfattning : Different sample preparation steps prior to a detection method are often essential in analytical chemistry. In this thesis, both static extractions and on-line coupled solid-phase extractions have been studied in combination with different detection techniques. LÄS MER
2. Mass Spectrometry-based Neuroproteomics : Deciphering the Human Brain Proteome
Sammanfattning : Mammalian brain is challenging to study due to its heterogeneity and complexity. However, recent advances in molecular imaging, genomics and proteomics have contributed significantly to achieve insights into molecular basis of brain function and pathogenesis of neurological disorders. LÄS MER
3. Occurrence of Traffic-Derived Microplastics in Different Matrices in the Road Environment
Sammanfattning : The prevalence of microplastic contamination has raised concerns about the potential risk and impact on the global environment. Traffic-derived microplastics, i.e., tire wear particles (TWP), polymer-modified bitumen, and road markings contribute to the emissions, and TWP are assumed to be one of the largest sources of microplastic emissions. LÄS MER
4. Selectivity in NMR and LC-MS Metabolomics : The Importance of Sample Preparation and Separation, and how to Measure Selectivity in LC-MS Metabolomics
Sammanfattning : Until now, most metabolomics protocols have been optimized towards high sample throughput and high metabolite coverage, parameters considered to be highly important for identifying influenced biological pathways and to generate as many potential biomarkers as possible. From an analytical point of view this can be troubling, as neither sample throughput nor the number of signals relates to actual quality of the detected signals/metabolites. LÄS MER
5. Novel microfluidic based sample preparation methods for rapid separation and detection of viable bacteria from blood for sepsis diagnostics
Sammanfattning : Sepsis is a serious medical condition characterized by a whole-body inflammatory response caused by bloodstream infection. The final stage of sepsis can lead to septic shock, multiple organ failure, and death. In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. LÄS MER