Sökning: "genes"
Visar resultat 11 - 15 av 4465 avhandlingar innehållade ordet genes.
11. Pancreatic Endocrine Tumourigenesis : Genes of potential importance
Sammanfattning : Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive. LÄS MER
12. Genes and brain tumors
Sammanfattning : Although brain tumors are rare and combined with other nervous system tumors account for ~ 2% of all cancers, they are the second most common type of pediatric cancer. The etiology of brain tumors, known as multifactorial traits, is poorly understood. LÄS MER
13. From Genes to Therapy : Modeling and Novel Therapeutic Strategies for Brain Tumors
Sammanfattning : Medulloblastoma is the most common malignant pediatric brain tumor and is molecularly divided into four subgroups – WNT, SHH, Group 3 and Group 4. Two thirds of medulloblastoma patients survive, but survivors often suffer from severe, lifelong side-effects. The MYCN oncogene is deregulated in many medulloblastoma patients. LÄS MER
14. Finding Genes for Schizophrenia
Sammanfattning : Schizophrenia is one of our most common psychiatric diseases. It severely affects all aspects of psychological functions and results in loss of contact with reality. No cure exists and the treatments available today produce only partial relief for disease symptoms. LÄS MER
15. Epigenetic Dysregulations in the Brain of Human Alcoholics : Analysis of Opioid Genes
Sammanfattning : Neuropeptides are special in their expression profiles restricted to neuronal subpopulations and low tissue mRNA levels. Genetic, epigenetic and transcriptional mechanisms that define spatiotemporal expression of the neuropeptide genes have utmost importance for the formation and functions of neural circuits in normal and pathological human brain. LÄS MER