Sökning: "psychiatric genetics"
Visar resultat 1 - 5 av 36 avhandlingar innehållade orden psychiatric genetics.
1. High-resolution Studies of mRNA Expression in Brain : A Search for Genes Differently Expressed in Schizophrenia
Sammanfattning : Gene expression differences between patients and controls can be used to find susceptibility genes and drug targets for a disease. High-resolution strategies are required because the differences between the investigated groups may be small and numerous factors may affect the mRNA quantity. LÄS MER
2. Pawsitive selection : Genetics of dog-human communication
Sammanfattning : Through domestication and recent selection, dogs have evolved a unique set of communicative skills to attract and redirect human attention. These social skills have not been seen to the same extent in socialised wolves and are therefore believed to have a significant genetic basis. LÄS MER
3. Microangiopathies of the human brain b immunohistochemical studies on extracellular matrix components in arterial vessels and endothelin
Sammanfattning : Microangiopathies may cause ischemic brain lesions and are of fundamental importance in vascular dementia. Risk factors include high age, hypertension, diabetes and Alzheimer's disease. LÄS MER
4. Methods from Statistical Computing for Genetic Analysis of Complex Traits
Sammanfattning : The goal of this thesis is to explore, improve and implement some advanced modern computational methods in statistics, focusing on applications in genetics. The thesis has three major directions.First, we study likelihoods for genetics analysis of experimental populations. LÄS MER
5. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood
Sammanfattning : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. LÄS MER