Sökning: "epigenetics"
Visar resultat 1 - 5 av 109 avhandlingar innehållade ordet epigenetics.
1. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood
Sammanfattning : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. LÄS MER
2. Networks in epigenetics
Sammanfattning : Networks are ubiquitous. It is only recently, we started exploring what purpose they serve in real world. Biological research supposedly has, and will be, benefited most from the network science because of inherent complexity embedded in its multilayered organization. LÄS MER
3. Genetics, epigenetics and functional mechanisms in inherited corneal and retinal dystrophies
Sammanfattning : Inherited eye disorders (IED) are groups of genetically and clinically heterogenous conditions affecting different tissues in the eye. IED are most often progressive with reduced vision or legal blindness as outcome. LÄS MER
4. On the role of genetic variation and epigenetics in hemostatic gene regulation
Sammanfattning : Many genetic variants have been identified to associate with circulating levels of hemostatic proteins and with thrombotic or hemorrhagic disorders. However, the underlying molecular mechanisms remain largely unknown. LÄS MER
5. Epigenetics of paediatric glioma stem cells; focusing on exosomes, miRNAs and DNA methylation
Sammanfattning : Tumours in the central nervous system are accountable for the majority of cancer-related deaths in children. Glioblastoma multiforme, one of the deadliest of the central nervous system tumours, is partly driven by glioma stem cells. The generation and maintenance of these cells is orchestrated by complex genetic and epigenetic mechanisms. LÄS MER