Sökning: "extracellular defense"

Visar resultat 1 - 5 av 76 avhandlingar innehållade orden extracellular defense.

  1. 1. Cellular Responses to Arsenite and Cadmium - Mechanisms of Toxicity and Defense in Saccharomyces cerevisiae

    Författare :Therese Jacobson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; arsenic; arsenite; cadmium; glutathione; extracellular defense; protein aggregation; chaperones; proteasome; Saccharomyces cerevisiae;

    Sammanfattning : All biological systems have to cope with a wide range of metals that are present in the environment. Metals can be essential or beneficial for life, inert or non-essential and toxic, often depending on their chemical form and concentration. Most organisms have evolved defense mechanisms in order to deal with toxic metals. LÄS MER

  3. 2. Defense-peptides against mycobacteria

    Författare :Charlotte M A Linde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antimicrobial peptides; NK-lysin; granulysin; PR-39; Mycobacterium;

    Sammanfattning : Several members of the genus Mycobacterium can cause serious infections in both man and animal. One of the world's most serious infectious diseases, tuberculosis, is caused by the pathogen Mycobacterium tuberculosis. Specific defense to tuberculosis/mycobacteriosis is dependent on the individual's ability to mount a proficient immune response. LÄS MER

  4. 3. On dysregulated inflammation and airway host defense

    Författare :Ravi K. V. Bhongir; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aiway inflammation; Chronic obstructive pulmonary disease COPD ; Cystic Fibrosis; Pseudomonas aeruginosa; DNase I;

    Sammanfattning : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. LÄS MER

  5. 4. Role of macrophage receptor MARCO in host defense

    Författare :Marko Sankala; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MARCO; innate immunity; scavenger receptor.;

    Sammanfattning : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. LÄS MER

  7. 5. Acute pancreatitis, from local defense to remote organ injury

    Författare :Hamid Akbarshahi; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; heparan sulfate; damage associated molecular patterns; toll-like receptor4; MyD88; IRF-3; acute lung injury; macrophages; transforming growth factor-beta; Smad;

    Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). LÄS MER