Sökning: "coated pellets"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden coated pellets.

  1. 1. Some aspects on the reduction of olivine pellets in laboratory scale and in an experimental blast furnace

    Författare :Jerker Sterneland; KTH; []
    Nyckelord :Olivine; pellets; pellet testing; reduction softening melting; MPBO; blast furnace; reduction; quenching; dissection; coating; sticking; coated pellets;

    Sammanfattning : The reduction behaviour of the olivine iron ore pellet MPBOwas studied in laboratory scale at KTH as well as in the LKABexperimental blast furnace. Initially, a newreduction-under-load, or so-called reduction/softening/melting,test equipment was developed. LÄS MER

  3. 2. Modelling of Drug Release from Reservoir and Matrix Formulations - Multiple Unit Dosage Forms and Swelling and Dissolving Matrix Systems

    Författare :Per Borgquist; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; swelling; XEDS; Chemical technology and engineering; Kemiteknik och kemisk teknologi; Polymer technology; biopolymers; Polymerteknik; Pharmaceutical and related technologies; Läkemedelsteknik och relaterad teknik; simulation; single pellet; single-unit release; SEM; reservoir system; poly ethylene oxide ; film-coated; matrix; mathematical model; diffusion; pellet shape; controlled release; polymer dissolution; modelling; ethyl cellulose; Coating; multiple-unit release;

    Sammanfattning : In this work, mathematical models have been developed describing drug release from film-coated reservoir systems as well as drug release and polymer dissolution from swelling and dissolving polymer tablets. The model derivation of both systems is based on a mechanistic approach. The model describing drug release from reservoir systems, i.e. LÄS MER

  4. 3. Characterization of the Mechanisms of Drug Release from Polymer-Coated Formulations using Experiments and Modelling

    Författare :Mariagrazia Marucci; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ethyl cellulose; Release mechanism; coating; polymer blend; modelling; ESPI; diffusion; osmotic pumping; SEM; single pellet; CLSM; hydroxypropyl cellulose; multiple-unit release;

    Sammanfattning : The main objectives of the work presented in this thesis were to develop new experimental methods to improve the understanding of the release mechanism from a coated formulation and to develop new mechanistic models to describe the release process for pellets coated with a semi-permeable film. Another aim was to characterize the release mechanism from a formulation coated with films made of a blend of a water-insoluble polymer, ethyl cellulose (EC), and a water-soluble polymer, hydroxypropyl cellulose (HPC). LÄS MER

  5. 4. Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release

    Författare :Åsa Tunón; Göran Alderborn; Michael E. Aulton; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; multiple unit tablets; extrusion-spheronisation; barrier-coating; modified drug release; pellet types; compaction; tablet properties; deformation; densification; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. LÄS MER

  7. 5. Mass Transport through Phase Separated Films - Effects of Ethyl Cellulose Molecular Weight on Cellulose Derivative Blends for Pharmaceutical Coatings

    Författare :Helene Andersson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Coating; Ethyl cellulose; Diffusion; Mass transport; Solvent evaporation; Molecular weight; Phase separation; Film; Hydroxypropyl cellulose; Polymer blend; Cellulose derivatives; Controlled release;

    Sammanfattning : Polymer blends are utilized for a variety of applications, not least in pharmaceutical coatings for controlled release of drugs. For instance, blends of ethyl cellulose (EC) and the water-soluble hydroxypropyl cellulose (HPC) can be used to coat drug pellets for oral extendedrelease formulations. LÄS MER