Sökning: "Controlled release"

Visar resultat 1 - 5 av 276 avhandlingar innehållade orden Controlled release.

  1. 1. Poly(Lactide-co-Glycolide) in Controlled-Release Pharmaceuticals - Release Mechanisms

    Författare :Susanne Fredenberg; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PLGA; Poly lactide-co-glycolide ; Release mechanism; Diffusion; Controlled Release; Degradation; Protein;

    Sammanfattning : Controlled-release formulations reduce the frequency of injections and better maintain plasma concentrations within the therapeutic window. Poly(D,L-lactide-co-glycolide) (PLG) is currently the most frequently used biodegradable polymer for this application. LÄS MER

  3. 2. Modification of microcapsules for controlled release

    Författare :Markus Andersson Trojer; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; block copolymer; coordination chemistry; polyelectrolyte multilayer; cross-linking; vibrational spectroscopy; electron paramagnetic resonance; imidazole; controlled release; colloidal stability; Microcapsule; quartz crystal microbalance with dissipation;

    Sammanfattning : Fouling of marine organisms such as algae and barnacles on the boat hull is an enormous problem for the shipping industry. The negative consequences for the society are both economical and environmental. To prevent fouling in general, biocides are typically incorporated directly into the paint. LÄS MER

  4. 3. Characterisation of an in vitro dissolution method for assessment of novel pulmonary drug delivery systems : With a focus on controlled release systems

    Författare :Irès van der Zwaan; Göran Frenning; Per Hansson; Rebecca Fransson; Alessandra Rossi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pulmonary drug delivery; in vitro dissolution; mechanistic model; controlled release; physiologically based biopharmaceutics modelling;

    Sammanfattning : Pulmonary drug delivery has been used for decades to treat local diseases like asthma. When using the pulmonary route to deliver drugs, several important lung features are being used, such as a large surface area available for absorption, high organ vascularization, and a thin blood-alveolar barrier. LÄS MER

  5. 4. Enhanced edible films of mixed biopolymers for controlled release

    Författare :Maria Petersson; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; acetem; phase separation; mechanical properties; hylon; edible rilm; release; starch; zein; water vapour premeability;

    Sammanfattning : In recent years there has been a growing interest and increased intensity of research in the area of edible films and coatings. Edible films and coatings can improve quality and shelf-life of food products by acting as barriers to e.g. moisture and oxygen, hence preventing dehydration and oxidative reactions. LÄS MER

  7. 5. Modelling of Drug Release from Reservoir and Matrix Formulations - Multiple Unit Dosage Forms and Swelling and Dissolving Matrix Systems

    Författare :Per Borgquist; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; swelling; XEDS; Chemical technology and engineering; Kemiteknik och kemisk teknologi; Polymer technology; biopolymers; Polymerteknik; Pharmaceutical and related technologies; Läkemedelsteknik och relaterad teknik; simulation; single pellet; single-unit release; SEM; reservoir system; poly ethylene oxide ; film-coated; matrix; mathematical model; diffusion; pellet shape; controlled release; polymer dissolution; modelling; ethyl cellulose; Coating; multiple-unit release;

    Sammanfattning : In this work, mathematical models have been developed describing drug release from film-coated reservoir systems as well as drug release and polymer dissolution from swelling and dissolving polymer tablets. The model derivation of both systems is based on a mechanistic approach. The model describing drug release from reservoir systems, i.e. LÄS MER