Sökning: "osmotic pumping"

Hittade 2 avhandlingar innehållade orden osmotic pumping.

  1. 1. Characterization of the Mechanisms of Drug Release from Polymer-Coated Formulations using Experiments and Modelling

    Författare :Mariagrazia Marucci; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ethyl cellulose; Release mechanism; coating; polymer blend; modelling; ESPI; diffusion; osmotic pumping; SEM; single pellet; CLSM; hydroxypropyl cellulose; multiple-unit release;

    Sammanfattning : The main objectives of the work presented in this thesis were to develop new experimental methods to improve the understanding of the release mechanism from a coated formulation and to develop new mechanistic models to describe the release process for pellets coated with a semi-permeable film. Another aim was to characterize the release mechanism from a formulation coated with films made of a blend of a water-insoluble polymer, ethyl cellulose (EC), and a water-soluble polymer, hydroxypropyl cellulose (HPC). LÄS MER

  3. 2. Ethyl Cellulose Membranes used in Modified Release Formulations

    Författare :Johan Hjärtstam; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; osmotic pumping; water permeability; drug release; reflectivity; ethyl cellulose; degree of substitution; mechanical strength;

    Sammanfattning : Ethyl cellulose (EC) is a commonly used polymer in modified drug release formulations. The general aim of the present study was to investigate release mechanisms through non-porous EC membranes with hydroxypropyl methyl cellulose (HPMC) contents ranging from 0 to 30% by weight. LÄS MER