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1. 1. Combinatorial Protein Engineering Of Affibody Molecules Using E. Coli Display And Rational Design Of Affibody-Based Tracers For Medical Imaging

   Författare :Ken G. Andersson; John Löfblom; Stefan Ståhl; Harald Kolmar; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; directed evolution; microbial display; E. coli; Affibody molecule; autotransporter; medical imaging; HER receptor family; Sortase A; Bioteknologi; Biotechnology;

   Sammanfattning : Directed evolution is today an established strategy for generation of new affinity proteins. This thesis describes the development of a cell-display method using Escherichia coli for directed evolution of Affibody molecules. LÄS MER