Sökning: "Thl"
Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet Thl.
1. Antibodies during pregnancy : Aspects on complications during pregnancy and complications related to transfusion
Sammanfattning : The fetus acquires half of its genetic infonnation from the father and represents a foreign graft in pregnancy. The overall mechanisms contributing to immunologic tolerance and successful pregancy still are an enigma. Accumulating results of immunologic research, however, offer an explanation for many events in pregnancy. LÄS MER
2. Immunopathogenesis and nasal tolerance in experimental autoimmune myasthenia gravis
Sammanfattning : Myasthenia gravis (MG) is a classical antibody-mediated autoimmune disease of the neuromuscular junction. Experimental autoimmune myasthenia gravis (EAMG), can be induced in susceptible rat or mouse strains by immunization with acetylcholine receptor (AChR) in complete Freund's adjuvant (CFA). LÄS MER
3. Modulation of experimental T cell autoimmunity in the nervous system with emphasis on nasal tolerance
Sammanfattning : Experimental autoimmune neuritis (EAN) and encephalomyelitis (EAE) are animal models of Guillian-Barre syndrome (GBS) and multiple sclerosis (MS), representing human demyelinating diseases of the peripheral nervous system (PNS) and central nervous system (CNS), respectively. CD4+ T cells recognizing myelin antigens and producing cytokines play central roles in the pathogenesis of both EAN and EAE and perhaps of GBS and MS. LÄS MER
4. Immunoregulatory differences between adult onset type 1 diabetes and latent autoimmune diabetes in adults (LADA)
Sammanfattning : Autoimmune diabetes is characterized by cell mediated autoimmunity against insulin producing beta cells in pancreatic islets. Type 1 diabetes is the major cause of diabetes in children and adolescents and is believed to be mediated by a Thl driven destruction of beta cells. LÄS MER
5. Development of IgG subclass antibodies to allergens in early childhood
Sammanfattning : Background: Immune responses to allergens in young children include both Thl and Th2 like immunity, which may regulate the secretion of IgG subclass antibodies differently. The time, route and level of exposure to an allergen, as well as maternally transferred immunity, may be decisive whether sensitisation or tolerance will ensue. LÄS MER