Sökning: "T cell receptor excision circles TRECs"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden T cell receptor excision circles TRECs.

1. 1. Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients

   Författare :Kristina Elgbratt; Göteborgs universitet; []
   Nyckelord :Inflammatory bowel diseaseInflammatory bowel disease; G?i2- - mice; dextran sodium sulfate; thymocytes; T cell receptor excision circles TRECs ; resent thymic emigrants;

   Sammanfattning : Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients Kristina Elgbratt Department of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy, G?teborg University, G?teborg Sweden Inflammatory Bowel Disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract, comprising ulcerative colitis and Crohn?s disease. LÄS MER

3. 2. Mode of delivery, epigenetic modulation and immune cell formation at birth

   Författare :Titus Schlinzig; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Birth by Cesarean section (CS) has been associated with a greater risk for immune disorders like allergy, asthma, type 1 diabetes, celiac disease, inflammatory bowel diseases, and cancer later in life. Although elective CS continues to increase rapidly, it is unclear if and how it may contribute to future health and disease. LÄS MER

4. 3. Methods and biomarkers for outcome prediction after allogeneic hematopoietic stem cell transplantation

   Författare :Darius Sairafi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Allogeneic hematopoietic stem cell transplantation (HSCT) is a potent immunotherapeutic procedure but its usability is limited by a high risk of serious complications. A prerequisite for timely initiation of preventive measures is the availability of predictive methods. LÄS MER

5. 4. Thymus dysfunction in the 22q11 deletion syndrome

   Författare :Jenny Lingman Framme; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 22q11.2 deletion syndrome; TREC; thymus;

   Sammanfattning : Introduction: The 22q11.2 deletion syndrome (22q11DS) is associated with heterogeneous clinical findings, including T-cell immunodeficiency resulting from thymus hypoplasia. LÄS MER

7. 5. Early childhood thymectomy - impact on immune function

   Författare :Judith Gudmundsdottir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immunologi; Thymus; Pediatric cardiac surgery; Congenital heart defect;

   Sammanfattning : Introduction: The thymus is the site of T cell maturation. Children born with a congenital heart defect often endure surgery early in life, and during surgery their thymus is routinely removed, as it blocks the surgeons access to the heart. LÄS MER