Sökning: "Medicin och hälsovetenskap Medicinska grundvetenskaper"
Visar resultat 1 - 5 av 3746 avhandlingar innehållade orden Medicin och hälsovetenskap Medicinska grundvetenskaper.
1. Prehospital Diagnosis and Oxygen Treatment in ST Elevation Myocardial Infarction
Sammanfattning : IntroductionPaper I: An Artificial Neural Network (ANN) was constructed to identify ST Elevation Myocardial Infarction (STEMI) and predict the need for Percutaneous Coronary Intervention (PCI). Paper II, III and IV: Studies suggest that O2 therapy may be harmful in STEMI patients. LÄS MER
2. Insulin Resistance : Causes, biomarkers and consequences
Sammanfattning : The worldwide increasing number of persons affected by largely preventable diseases like diabetes demands better prevention and treatment. Insulin is required for effective utilisation of circulating nutrients. LÄS MER
3. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota
Sammanfattning : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. LÄS MER
4. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection
Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER
5. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities
Sammanfattning : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. LÄS MER