Sökning: "peripheral blood mononuclear cells"

Visar resultat 1 - 5 av 182 avhandlingar innehållade orden peripheral blood mononuclear cells.

  1. 1. Inhibition of T cell responses to autoantigens and allergens by CD25+ regulatory T cells from thymus, cord and adult blood

    Författare :Kajsa Wing; Göteborgs universitet; []
    Nyckelord :Tolerance; CD25 regulatory T cells; adult peripheral blood; cord blood; thymus; autoimmune disease; allergy;

    Sammanfattning : Autoimmune diseases and allergies are a growing problem in the western world today. Tolerance is primarily established by clonal deletion in the thymus. Despite this auto-reactive T cells are normally present in most individuals, which suggests that mechanisms of peripheral tolerance operate to silence potentially pathogenic T cells. LÄS MER

  3. 2. On HIV-1 restriction in human dendritic cells and peripheral blood mononuclear cells

    Författare :Venkatramanan Mohanram; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dendritic cells (DCs) are one of the first cells to encounter HIV-1 during sexual transmission. They may transmit the virus to CD4+ T-cells either locally or in the draining lymph nodes. In the present work, we have focused the studies on monocyte derived DCs. Upon DC maturation, HIV-1 replication is restricted in these DCs. LÄS MER

  4. 3. Lactobacilli- and Staphylococcus aureus mediated modulation of immune responses in vitro

    Författare :Yeneneh Haileselassie; Eva Sverremark-Ekström; Huub Savelkoul; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; lactobacilli; staphylococcus aureus; dendritic cells; retinoic acid; epithelial cells; T cells; immunologi; Immunology;

    Sammanfattning : The human gut harbors a vast number of microbes. These microbes are not passive bystanders. They are important in modulating the immune system. We have previously shown that early colonization with lactobacilli and Staphylococcus (S. LÄS MER

  5. 4. IL-25 and B cells in atherosclerosis

    Författare :Polyxeni Mantani; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-25; B cells; ILC2s; IL-5; anti-PC IgM; atherosclerosis; stroke; cardiovascular events;

    Sammanfattning : Atherosclerosis is a chronic inflammatory disease of medium and large vessels of the body which is mainly characterized by the formation of lipid rich plaques within the arterial tissue. It is the most common cause of cardiovascular disease leading to clinical manifestations of coronary artery and cerebrovascular disease. LÄS MER

  7. 5. Regulation of innate and acquired immunity in infants by commensal bacteria

    Författare :Helen Karlsson; Göteborgs universitet; []
    Nyckelord :intestinal microflora; commensal; antigen-presenting cells; dendritic cells; CD25 regulatory T cells; allergy; infants; Staphylococcus aureus;

    Sammanfattning : The incidence of atopic diseases in children is steadily increasing in the industrialised world along with an improved hygienic lifestyle. The gastrointestinal flora may be of specific importance for the proper maturation of the immune system and for the induction of tolerance, in which CD25+ regulatory T cells (Tregs) play a crucial role. LÄS MER