Sökning: "Lateral Stability Control"

Visar resultat 21 - 25 av 49 avhandlingar innehållade orden Lateral Stability Control.

  1. 21. SOD1´s Law : An Investigation of ALS Provoking Properties in SOD1

    Författare :Roberth Byström; Gerhard Gröbner; Stefan Marklund; Mikael Oliveberg; Bengt-Harald Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; amyotrophic lateral sclerosis; SOD1; protein folding; membrane interaction; aggregates; survival time; repulsive charge; Biochemistry; Biokemi;

    Sammanfattning : Proteins are the most important molecules in the cell since they take care of most of the biological functions which resemble life. To ensure that everything is working properly the cell has a rigorous control system to monitor the proper function of its proteins and sends old or dysfunctional proteins for degradation. LÄS MER

  3. 22. SOD1 prions transmit templated aggregation and fatal ALS-like disease

    Författare :Elaheh Ekhtiari Bidhendi; Thomas Brännström; Stefan L. Marklund; Peter M. Andersen; Inger Nennesmo; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; amyotrophic lateral sclerosis; SOD1; prion; neurodegeneration; strain; seeding; protein misfolding; protein aggregation; propagation; transgenic mice; Pathology; patologi; Neurology; neurologi;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is an adult-onset fatal neurodegenerative disease characterized by a progressive degeneration of the upper and lower motor neurons. The resulting paresis begins focally, usually in one muscle, and spreads contiguously, leading to muscle wasting, progressive paralysis and eventually death. LÄS MER

  4. 23. Aspects of oral implant technology and osseointegration

    Författare :Rainde Naiara Rezende de Jesus; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; oral implants; surface topography; surface roughness; surface energy; surface wettability; hydrophilicity; macrogeometry; implant body; thread design; surgical protocol; oversized drilling; osseointegration; bone-to-implant contact; bone density; primary implant stability; insertion torque; removal torque; removal energy; connection stiffness; osteoclasts; RAW264.7 cells; gene expression;

    Sammanfattning : Behandling med käkbensförankrade tandimplantat är en vanlig metod för att ersätta förlorade tänder hos helt och partiellt tandlösa patienter. Trots att implantatbehandling uppvisar en långsiktigt hög lyckande- och överlevnadsfrekvens (90–95% efter 10 år) så förekommer implantatförluster och marginal benförlust kring implantaten under det första året efter insättning och/eller belastning, vilket kan försämra det estetiska resultatet. LÄS MER

  5. 24. Neural mechanisms for the control of posture, locomotion and steering : a behavioral, electrophysiological and modeling study in lamprey

    Författare :Patriq Fagerstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :reticulospinal; vestibular system; spinal cord; central pattern generator; reciprocal inhibition; fictive locomotion; fictive turning; electron microscopy; computer simulation; lamprey; dorsal fin;

    Sammanfattning : When animals move around interacting with the environment, the nervous system has to solve several tasks simultaneously in order to produce and control the movements - notably propulsion, posture, balance, and associated movements. Basic motor tasks are controlled by neuronal networks organized into central pattern generators (CPGs) and reflexes, located in the spinal cord and brainstem. LÄS MER

  7. 25. Metabolomics studies of ALS : a multivariate search for clues about a devastating disease

    Författare :Anna Wuolikainen; Peter M Andersen; Henrik Antti; Stefan L Marklund; Thomas Moritz; Thomas Hankemeier; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyotrophic lateral sclerosis ALS ; motor neuron disease; Lou Gehrig’s disease; human disease; CSF; biomarkers; metabolomics; metabonomics; chemometrics; design of experiments; multivariate analysis.; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS), also known as Charcot’s disease, motor neuron disease (MND) and Lou Gehrig’s disease, is a deadly, adult-onset neurodegenerative disorder characterized by progressive loss of upper and lower motor neurons, resulting in evolving paresis of the linked muscles. ALS is defined by classical features of the disease, but may present as a wide spectrum of phenotypes. LÄS MER