Sökning: "CSF"

Visar resultat 1 - 5 av 526 avhandlingar innehållade ordet CSF.

  1. 1. Analysis of ICP pulsatility and CSF dynamics : the pulsatility curve and effects of postural changes, with implications for idiopathic normal pressure hydrocephalus

    Författare :Sara Qvarlander; Anders Eklund; Jan Malm; Richard Birgander; Martin U Schuhmann; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cerebrospinal fluid; CSF dynamics; Intracranial pressure; Pulse pressure; Normal pressure hydrocephalus; Posture; Predictive tests; Mathematical modelling; Magnetic resonance imaging; Infusion tests;

    Sammanfattning : The volume defined by the rigid cranium is shared by the brain, blood and cerebrospinal fluid (CSF). With every heartbeat the arterial blood volume briefly increases and venous blood and CSF are forced out of the cranium, leading to pulsatility in CSF flow and intracranial pressure (ICP). LÄS MER

  3. 2. Granulopoietic growth factors. Cytokine and cellular regulation of GM-CSF and G-CSF production

    Författare :Stig Lenhoff; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocytes; endothelial cells; GM-CSF; G-CSF; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Sammanfattning : Granulocyte-macrophage- (GM-) and granulocyte- (G-) colony stimulating factor (CSF) are important cytokines in the regulation of hematopoiesis and for the function of mature blood cells. They are also involved in the cytokine network regulating the inflammatory and immune response. LÄS MER

  4. 3. The postsynaptic protein neurogranin: a new item in the Alzheimer’s disease biomarker toolbox

    Författare :Hlin Kvartsberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CSF; brain tissue; Alzheimer s disease; biomarker; neurogranin;

    Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia affecting more than 50 million people worldwide today and is characterised by progressive cognitive decline. One of the earliest events in AD, which is also closely related to neuronal loss and the degree of dementia, is synaptic degeneration. LÄS MER

  5. 4. Biomarkers as Monitors of Drug Effect, Diagnostic Tools and Predictors of Deterioration Rate in Alzheimer’s Disease

    Författare :Malin Degerman Gunnarsson; Lena Kilander; Hans Basun; Jan Marcusson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; biomarkers; CSF; PIB PET; amyloid-beta; tau; rapid cognitive decline; dying in severe dementia; mortality; neuropsychological tests; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Decreased amyloid-ß42 (Aß42), increased total tau (t-tau) and phosphorylated tau (p-tau) in cerebrospinal fluid (CSF) reflect histopathological core changes in the most common dementia disorder, Alzheimer’s disease (AD). They discriminate AD from healthy controls and predict conversion to AD with a relatively high accuracy. LÄS MER

  7. 5. Investigation of immunological preconditions in MS patients "MS immunopathic trait"

    Författare :Sara Haghighi; Göteborgs universitet; []
    Nyckelord :multiple sclerosis; siblings; CSF; oligoclonal; cytokine; sulfatide; genetics; trait;

    Sammanfattning : We examined 47 MS patients, 47 healthy siblings and 50 healthy unrelated individuals with blood and CSF analysis and found that 19 % (9/47) of healthy siblings of clinically definite multiple sclerosis patients had an intrathecal immunological reaction to ¡Ý 2 CSF-enriched OCB, in contrast to 4% (2/50) of the unrelated healthy controls. We termed this condition ¡°MS immunopathic trait¡±. LÄS MER