Sökning: "Interleukin-1 beta"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Interleukin-1 beta.
1. Genetic variations in the NALP3 inflammasome: a susceptibility factor for inflammatory diseases
Sammanfattning : Innate immunity has received impressive attention in the past decade owing to the discovery of the Toll like receptors (TLRs) and the NOD-like receptors (NLRs). While the TLRs specialize in fighting microbes at the cell surface, the NLRs complement by detecting and responding to intracellular microbes. LÄS MER
2. Studies of cytokine mediated regulation of central nervous functions : role of prostaglandins
Sammanfattning : The communication between the immune system and the central nervous system (CNS) results in an array of centrally regulated illness responses, including fever and increased hypothalamus-pituitary-adrenal (HPA) axis activity. The mechanisms by which the immune system signals the brain across the blood-brain barrier have not been completely elucidated, but proinflammatory cytokines, like interleukin-1 (IL-1), are believed to act as important mediators. LÄS MER
3. Pain and radiographic changes of the arthritic temporomandibular joint : relation to cytokines in synovial fluid and plasma
Sammanfattning : In patients with rheumatoid arthritis and other inflammatory joint diseases, radiographic changes of the TMJ are frequently observed. Common symptoms of TMJ involvement are pain at rest and on movement of the jaw. LÄS MER
4. Mechanisms of defective insulin secretion in type 2 diabetes
Sammanfattning : Defective insulin secretion from the pancreatic B-cells is a central feature in type 2 diabetes (T2D). There is a strong hereditary component in type T2D, but the underlying pathophysiology remains largely unknown. LÄS MER
5. Effects of imidazoline compounds on intracellular CA2+ and apoptosis
Sammanfattning : Cytoplasmic free Ca2+ concentration ([Ca2+]i) plays a pivotal role in the regulation of insulin release from the pancreatic beta-cell. [Ca2+]i is also important in the control of apoptosis. LÄS MER