Sökning: "central nervous system"

Visar resultat 1 - 5 av 779 avhandlingar innehållade orden central nervous system.

  1. 1. Cyanide and central nervous system : a study with focus on brain dopamine

    Författare :Gudrun Cassel; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CNS; cyanide; dopaminergic system; convulsions; receptor binding; tyrosine hydroxylase; monoamine oxidase; extracellular release; inositol phosphate; GABA; GAD;

    Sammanfattning : The brain is a major target site in acute cyanide intoxication, as indicated by several symptoms and signs. Cyanide inhibits the enzyme cytochrome oxidase. This inhibition causes impaired oxygen utilization in all cells affected, severe metabolic acidosis and inhibited production of energy. LÄS MER

  3. 2. Neuron-glial Interaction in the Developing Peripheral Nervous System

    Författare :Mikael Corell; Åsa Fex Svenningsen; Klas Kullander; Helgi Schöith; Heape Anthony; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schwann cell; nonmyelinating Schwann cell; myelinating Schwann cell; development; proliferation; differentiation; myelin; neural stem cell; central nervous system; peripheral nervous system; enteric nervous system; N-cadherin; GABA; GAD; GABA B receptor; baclofen; CGP55485; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Sammanfattning : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. LÄS MER

  4. 3. Central nervous system targets for micturition control

    Författare :Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

    Sammanfattning : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. LÄS MER

  5. 4. Nasal administration of compounds active in the central nervous system : Exploring the olfactory system

    Författare :Maria Dahlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Nasal administration; olfactory pathway; cerebrospinal fluid; autoradiography; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : The nasal administration of drugs offers advantages over administration by intravenous injection. Drugs can be rapidly absorbed through the nasal mucosa, resulting in a rapid onset of action, and also avoiding degradation in the gastrointestinal tract and first-pass metabolism in the liver. LÄS MER

  7. 5. Alphaherpesvirus infections of the central nervous system – Biomarkers, diagnostics and antiviral therapy

    Författare :Johan Lindström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpesviruses; central nervous system; facial paralysis; cerebrospinal fluid; biomarkers; acyclovir; neurotoxicity; syndromic testing;

    Sammanfattning : Abstract Herpesviruses predate the evolution of humans and are globally ubiquitous. Herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and varicella-zoster virus (VZV) establish latency in neuronal tissue and may cause infections in the central nervous system (CNS). LÄS MER