Sökning: "In-vitro simulations"

Visar resultat 21 - 25 av 57 avhandlingar innehållade orden In-vitro simulations.

  1. 21. Development and evaluation of optical techniques for tumour detection

    Författare :Charlotta Lindquist; Atomfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Different optical methods for tumour detection have been studied. Interference between photon density waves has been examined with the aim of investigating the potential of this technique for optical transillumination diagnostics. LÄS MER

  3. 22. Toward celiac-safe foods - Investigation of the interaction between transglutaminase 2 and gluten

    Författare :Niklas Engström; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gliadin; Caco-2 cells; transglutaminase 2; ileostomy subjects; ascorbyl palmitate; gluten; gluten digestion; TG2; zinc; celiac disease; gluten intolerance; extrusion cooking;

    Sammanfattning : Celiac disease, a chronic autoimmune enteropathy, may develop in genetically predisposed individuals upon ingestion of gluten proteins found in wheat, barley, and rye. Overall prevalence of celiac disease is increasing and it currently affects around 1% of the population. LÄS MER

  4. 23. Development of an Anisotropic Finite Element Head Model for Traumatic Brain Injury Prediction

    Författare :Chiara Giordano; Svein Kleiven; Songbai Ji; KTH; []
    Nyckelord :Axonal Strain; Brain Anisotropy; Traumatic Brain Injury; Finite Element Analysis; Brain Tissue; Constitutive Modeling.; Medical Technology; Medicinsk teknologi;

    Sammanfattning : Traumatic brain injury (TBI) is a worldwide health care problem with very high associatedmorbidity and mortality rates. In particular, the diagnosis of TBI is challenging: symptomsoverlap with other pathologies and the injury is typically not visible with conventionalneuroimaging techniques. LÄS MER

  5. 24. Pharmacokinetic and Pharmacodynamic Modeling of Antibiotics and Bacterial Drug Resistance

    Författare :Ami Fazlin Syed Mohamed; Lena Friberg; Teresa Dalla Costa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; antibiotics; resistance; combination; Gram-negative bacteria; gentamicin; colistin; meropenem; newborn infants; critically ill patients; Infectious Diseases; Infektionssjukdomar; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : Exposure to antibiotics is an important factor influencing the development of bacterial resistance.  In an era where very few new antibiotics are being developed, a strategy for the development of optimal dosing regimen and combination treatment that reduces the rate of resistance development and overcome existing resistance is of utmost importance. LÄS MER

  7. 25. The Utility of Ultrasmall Superparamagnetic Iron Oxide Contrast Agents for Cardiovascular Magnetic Resonance Imaging

    Författare :Lars Johansson; Håkan Ahlström; Hans-Jørgen Smith; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic resonance imaging; Contrast agent; Iron Oxide; Cardiovascular; Radiologisk forskning; Radiological research; Radiologisk forskning;

    Sammanfattning : The purpose of this thesis was to investigate the utility of the Ultrasmall Superparamagnetic Iron Oxide Particle (USPIO), NC100150 Injection for assessment of macro- and microvascular morphology and function using magnetic resonance imaging. The feasibility of NC100150 Injection was tested for the following applications: Coronary angiography, Thrombus detection, Cardiac function, Myocardial perfusion, Assessment of myocardial blood volume and water exchange and finally assessment of endothelial integrity of the myocardium. LÄS MER