Sökning: "Axonal Strain"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Axonal Strain.
1. Definition of axonal injury tolerances across scales : A computational multiscale approach
Sammanfattning : Traumatic brain injury (TBI) is today regarded as a global health challenge. Revealing how external mechanical loads translate into tissue and cellular damage is necessary, not only for the development of better preventive measures, but also for the definition of treatments that could spare the patients from suffering TBI's devastating consequences. LÄS MER
2. Development of an Anisotropic Finite Element Head Model for Traumatic Brain Injury Prediction
Sammanfattning : Traumatic brain injury (TBI) is a worldwide health care problem with very high associatedmorbidity and mortality rates. In particular, the diagnosis of TBI is challenging: symptomsoverlap with other pathologies and the injury is typically not visible with conventionalneuroimaging techniques. LÄS MER
3. Finite Element and Neuroimaging Techniques toImprove Decision-Making in Clinical Neuroscience
Sammanfattning : Our brain, perhaps the most sophisticated and mysterious part of the human body, to some extent, determines who we are. However, it’s a vulnerable organ. When subjected to an impact, such as a traffic accident or sport, it may lead to traumatic brain injury (TBI) which can have devastating effects for those who suffer the injury. LÄS MER
4. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration
Sammanfattning : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. LÄS MER
5. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease
Sammanfattning : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. LÄS MER