Sökning: "Gun Frisk"

Hittade 5 avhandlingar innehållade orden Gun Frisk.

  1. 1. Radioimmunoassays of antibodies to enteroviruses : applications in myopericarditis and in diabetes mellitus

    Författare :Gun Frisk; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Enterovirus Infections of β-Cells : A Mechanism of Induction of Type 1 Diabetes?

    Författare :Anna-Karin Berg; Gun Frisk; Torsten Tuvemo; Arne Andersson; Merja Roivainen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; enterovirus; type 1 diabetes; β-cells; human pancreatic islets; picornavirus; chemokines; nitric oxide; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Sammanfattning : The process of β-cell destruction that leads to type 1 diabetes (T1D) is incompletely understood and it is believed to be a result of both genetic and environmental factors. Enterovirus (EV) infections of the β-cells have been proposed to be involved, however, the effects of EV infections on human β-cells have been little investigated. LÄS MER

  4. 3. Studies of the Effect of Enterovirus Infection on Pancreatic Islet Cells

    Författare :Asma Basheir Elshebani; Gun Frisk; Heiki Hyöty; Uppsala universitet; []
    Nyckelord :Medical sciences; type 1 diabetes; Human pancreatic islets; β-cells; chemokines; enterovirus; MEDICIN OCH VÅRD;

    Sammanfattning : Enterovirus (EV) infections have been associated with the pathogenesis of Type 1 Diabetes (T1D). However, the pathway(s) by which EV may induce or accelerate diabetes is not well understood. LÄS MER

  5. 4. Inflammatory Mediators and Enterovirus Infections in Human Islets of Langerhans

    Författare :Annika Moëll; Gun Frisk; Olle Korsgren; Bo Nilsson; Outi Vaarala; Uppsala universitet; []
    Nyckelord :Immunology; diabetes; islets of Langerhans; enterovirus; inflammatory mediators; cytokines; nicotinamide; Immunologi;

    Sammanfattning : Type 1 diabetes (T1D) is due to a selective loss of the insulin producing β-cells. However, the process responsible for this loss is still unknown. There is accumulating evidence that enteroviruses (EVs) are involved in T1D. In addition to direct virus-induced cytolysis, EVs could facilitate β-cell destruction by inducing inflammatory cytokines. LÄS MER

  7. 5. Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans

    Författare :Oskar Skog; Gun Frisk; Olle Korsgren; Åke Lernmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Enterovirus; Coxsackievirus; Innate immunity; Pancreatic islets; Islet function; Medicinsk vetenskap; Medical Science;

    Sammanfattning : This thesis focuses on enteroviral effects on human pancreatic islets. Most knowledge of viral effects on host cells relies on studies of immortalized cell lines or animal models. The islets represent a fundamentally different and less well studied cellular host. Also, enterovirus has been implicated in the etiology of type 1 diabetes (T1D). LÄS MER