Sökning: "DNA polymorphisms"

Visar resultat 21 - 25 av 153 avhandlingar innehållade orden DNA polymorphisms.

  1. 21. Mechanisms of microbial-host interaction during asymptomatic bacteriuria

    Författare :Jenny Grönberg Hernandez; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asymptomatic bacteriuria; Urinary tract infection; Escherichia coli 83972; IRF3; TLR4; Evolution; host response; promoter polymorphisms; transcription; P fimbriae; Type 1 fimbriae;

    Sammanfattning : Urinary tract infections (UTIs) present an interesting and relevant model for studying microbial adaptation. After establishing significant numbers, the bacteria either cause severe disease, or an asymptomatic carrier state resembling the normal flora at other mucosal sites. LÄS MER

  3. 22. Wilms' tumor gene 1 in different types of cancer

    Författare :Xingru Li; Aihong Li; Karin Nylander; Eva Lundin; Xiaolian Gu; David M. Loeb; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WT1; AML; MRD; ccRCC; SNPs; DNA methylation; SCCHN; p63; Clinical Chemistry; klinisk kemi;

    Sammanfattning : The Wilms’ tumor gene 1 (WT1) was first reported as a tumor suppressor gene in Wilms’ tumor. However, later studies have shown the oncogenic properties of WT1 in a variety of tumors. It was recently proposed that WT1 was a chameleon gene, due to its dual functions in tumorigenesis. LÄS MER

  4. 23. From DNA to CBT : an investigation psychological therapy response and genetics

    Författare :Evelyn Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Social anxiety disorder, panic disorder, and major depressive disorder are common, disabling, and heritable disorders. The first line of treatment for all anxiety disorders and mild to moderate depression is cognitive behavior therapy (CBT). LÄS MER

  5. 24. Improved human papillomavirus DNA typing methods and biology of cervival cancer

    Författare :Biying Zheng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical cancer; human papillomavirus; Pyrosequencing; chemokine receptors; adenoassociated virus; biomarkers; and cell cycle checkpoint.;

    Sammanfattning : Cervical cancer is the second most common cancer among women worldwide. Persistent HPV has been identified as a main risk factor in cervical cancer development. Oncoproteins E6 and E7 of highrisk HPV interact with cellular proteins, subverting cell cycle checkpoint, inducing carcinogenesis. LÄS MER

  7. 25. Computational statistical methods for genotyping biallelic DNA markers from pooled experiments

    Författare :Camille Clouard; Carl Nettelblad; Lars Rönnegård; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The information conveyed by genetic markers such as Single Nucleotide Polymorphisms (SNPs) has been widely used in biomedical research for studying human diseases, but also increasingly in agriculture by plant and animal breeders for selection purposes. Specific identified markers can act as a genetic signature that is correlated to certain characteristics in a living organism, e. LÄS MER