Sökning: "Xiaolian Gu"

Hittade 3 avhandlingar innehållade orden Xiaolian Gu.

  1. 1. p63 and epithelial homeostasis : studies of p63 under normal, hyper-proliferative and malignant conditions

    Författare :Xiaolian Gu; Karin Nylander; Antonio Costanzo; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; p63; psoriasis; SCCHN; epithelium; homeostasis; Pathology; Patologi; patologi; Pathology;

    Sammanfattning : Background: The p63 gene is a member of the p53 transcription factor family and can produce six different proteins using two promoters and differential splicing. Expression of p63 is required for proper formation of epithelial tissues. LÄS MER

  3. 2. Wilms' tumor gene 1 in different types of cancer

    Författare :Xingru Li; Aihong Li; Karin Nylander; Eva Lundin; Xiaolian Gu; David M. Loeb; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WT1; AML; MRD; ccRCC; SNPs; DNA methylation; SCCHN; p63; Clinical Chemistry; klinisk kemi;

    Sammanfattning : The Wilms’ tumor gene 1 (WT1) was first reported as a tumor suppressor gene in Wilms’ tumor. However, later studies have shown the oncogenic properties of WT1 in a variety of tumors. It was recently proposed that WT1 was a chameleon gene, due to its dual functions in tumorigenesis. LÄS MER

  4. 3. Squamous cell carcinoma of the head and neck, focusing on Epstein-Barr-virus, programmed cell death ligand 1 and serum lipoproteins

    Författare :Torben Wilms; Karin Nylander; Xiaolian Gu; Linda Boldrup; Keith Hunter; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oral tongue cancer; squamous cell carcinoma; head and neck; Epstein Barr Virus; PD-L1; lipoprotein; Oncology; onkologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi; Pathology; patologi; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; immunologi; Immunology;

    Sammanfattning : Background: Squamous cell carcinoma of the head and neck (SCCHN)comprises a large group of tumours including the oral cavity and nasopharyngealarea, and typically affects older males in association with alcohol/tobacco usage.Within the oral cavity, the mobile tongue is the most common site for tumourdevelopment. LÄS MER