Sökning: "Contractile unit"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Contractile unit.

1. 1. Mechanisms Underlying Intensive Care Unit Muscle Wasting : Intervention Strategies in an Experimental Animal Model and in Intensive Care Unit Patients

   Författare :Monica Llano-Diez; Lars Larsson; Marco Sandri; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute quadriplegic myopathy; intensive care unit; myosin; regulation of contraction; muscle atrophy; mechanical loading; mobilization; Clinical Neurophysiology; Klinisk neurofysiologi;

   Sammanfattning : Critically ill patients admitted to the intensive care unit (ICU) commonly develop severe muscle wasting and weakness and consequently impaired muscle function. This not only delays respirator weaning and ICU discharge, but has deleterious effects on morbidity, mortality, financial costs, and quality of life of survivors. LÄS MER

3. 2. Mechanochemical Modeling of Smooth Muscle Activation

   Författare :Sae-Il Murtada; Gerhard A. Holzapfel; Robert McMeeking; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biomechanics; Muscle contraction; Smooth muscle; Contractile unit; Filament overlap; Intracellular calcium; Carotid artery; Mathematical model;

   Sammanfattning : Smooth muscle has an important role in several physiological processes, where it regulates the wall tension and the size of hollow organs. In blood vessels, the contraction and relaxation of smooth muscle contribute to the mechanical stability of the vessel wall and determines the diameter. LÄS MER

4. 3. Molecular And Cellular Networks in Critical Illness Associated Muscle Weakness : Skeletal Muscle Proteostasis in the Intensive Care Unit

   Författare :Varuna Chaminda Banduseela; Lars Larsson; Gustavo Nader; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chaperones; autophagy; intensive care unit; heat shock proteins; protein synthesis; proteostasis; ER stress; gene expression; sepsis; neuromuscular blockers; corticosteroids; immobilisation; mechanical ventilation; Molekylär cellbiologi; Molecular Cellbiology; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Critical illness associated muscle weakness and muscle dysfunction in intensive care unit (ICU) patients lead to severe morbidity and mortality as well as significant adverse effect on quality of life. Immobilization, mechanical ventilation, neuromuscular blocking agents, corticosteroids, and sepsis have been implicated as important risk factors, but the underlying molecular and cellular mechanisms remain unclear. LÄS MER

5. 4. Classification of muscle stretch receptor afferents in humans

   Författare :Benoni B. Edin; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Muscle spindles; Golgi tendon organs; Classification of muscle receptors; Microneurography; Human hand; Stretch sensitization; Voluntary contraction; Static position sensitivity; Fusimotor control;

   Sammanfattning : The response patterns of human stretch receptors in the finger extensor muscles of the forearm were studied using the microneurography technique. Single-unit recordings were obtained from one-hundred and twenty-four afferents. LÄS MER

7. 5. Identification of single motor units in ultrafast ultrasound image sequences of voluntary skeletal muscle contractions

   Författare :Robin Rohlén; Christer Grönlund; Jun Yu; Dario Farina; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ultrafast ultrasound; motor units; decomposition; skeletal muscle; voluntary contractions; electromyography; twitch; imaging;

   Sammanfattning : The central nervous system controls human force production by successive recruitment of motor units in the skeletal muscles and changing their neural firing rate. The motor unit comprises a motoneuron, its innervated muscle fibers, and its axons. LÄS MER