Sökning: "Christos Ouzounis"

Hittade 2 avhandlingar innehållade orden Christos Ouzounis.

1. 1. The evolution of ribonucleotide reductases

   Författare :Daniel Lundin; Anthony Poole; Britt-Marie Sjöberg; Christos Ouzounis; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; ribonucleotide reductase; horizontal gene transfer; phylogeny; protein classification; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

   Sammanfattning : Ribonucleotide reductase (RNR) catalyses the transformation of RNA building blocks, ribonucleotides, to DNA building blocks, deoxyribonucleotides. This is the only extant reaction pathway for de novo synthesis of DNA building blocks and the enzyme is thus necessary for life. RNR is found in all but a few organisms. LÄS MER

3. 2. Data integration for robust network-based disease gene prediction

   Författare :Gabriel Östlund; Erik Sonnhammer; Christos Ouzounis; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

   Sammanfattning : For many complex diseases the cause/mechanism can be tied not to a single gene and in order to cope with the complexity a systems wide approach is needed. By combining evidence indicative of functional association it is possible to infer networks of protein functional coupling. LÄS MER