Sökning: "AMP-activated protein kinase"
Visar resultat 1 - 5 av 23 avhandlingar innehållade orden AMP-activated protein kinase.
1. AMP-activated protein kinase in adipose tissue
Sammanfattning : The AMP-activated protein kinase (AMPK) is a ubiquitously expressed kinase, which is activated in response to depletion of cellularenergy levels. Once active, it functions to alter cellular metabolism in a way that leads to restoration of energy levels. Therefore,AMPK is described as the key regulator of cellular energy homeostasis. LÄS MER
2. AMP-activated protein kinase : the connection between exercise and type II diabetes
Sammanfattning : Skeletal muscle insulin resistance is a hallmark feature of Type 2 diabetes. Physical exercise/muscle contraction elicits an insulin-independent increase in glucose transport and perturbation of this pathway can bypass defective insulin signaling. LÄS MER
3. Skeletal muscle metabolic flexibility : the roles of AMP-activated protein kinase and calcineurin
Sammanfattning : Skeletal muscle fibers differ considerably in their metabolic and physiological properties. The metabolic properties of skeletal muscle display a high degree of flexibility which adapts to various physiological demands by shifting energy substrate metabolism. LÄS MER
4. Global Regulation of Snf1 in Saccharomyces cerevisiae: A case study of experimental systems biology
Sammanfattning : Cells commonly face environmental changes and have evolved various regulatory mechanisms to adjust their metabolism accordingly. One such key regulator in S. cerevisiae is the Snf1 kinase, which belongs to the conserved AMP-activated protein kinase (AMPK) family in all eukaryotes. LÄS MER
5. LKB1 signaling pathways in adipocytes - Focus on the AMPK-related kinase SIK2
Sammanfattning : Adipose tissue does not only store and release energy in response to hormones, it is also known as an endocrine organ, secreting important factors and hormones that influence for example appetite and insulin sensitivity. The association of type 2 diabetes with obesity has been known for quite some time. LÄS MER