Sökning: "tumor vaccine"

Visar resultat 21 - 25 av 44 avhandlingar innehållade orden tumor vaccine.

  1. 21. Strengthening the pillars of cancer immunotherapy

    Författare :Maarten Alexander Ligtenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The treatment of disease in cancer patients by harnessing the potent mechanisms that exist within the immune system is not a novel approach, and has been first attempted more than a century ago. During the major part of this century cancer immunotherapy has been relegated to the periphery of standard care for patients. LÄS MER

  3. 22. The HER2/neu oncoprotein and dendritic cells in immunity against tumors

    Författare :Yang Rongcun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HER2 neu; dendritic cells; ovarian carcinoma; apoptosis;

    Sammanfattning : It is now well established that small peptide epitopes bound to the major histocompatibility complex (MHC), derived from processed proteins synthesized by the tumor cells, can be recognized as antigens by cytotoxic T lymphocytes (CTLs). A number of tumor antigens recognized by CTLs on human melanomas have been defined, but less is known about antigens from other tumor types. LÄS MER

  4. 23. On lymph node based immunotherapy of cancer

    Författare :Lu Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer Immunotherapy based on one’s own immune system to fight cancer is emerging as an important treatment option for advanced stage diseases. The earliest attempts of cancer therapy based on the provocation of the immune system with infectious agents can be traced back to the 18th century, and the field of immunotherapy has since developed into three main groups: cellular-, antibody- and cytokine- therapies. LÄS MER

  5. 24. Development and evaluation of new therapeutic interventions for chronic hepatitis C virus infection

    Författare :Fredrik Holmström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The hepatitis C virus (HCV) is a major global health problem with around 130-150 million individuals chronically infected and it is estimated that 2 millions are newly infected each year. The HCV infection is one of the major causes of liver disease and the infection is characterized by a slow and silent progression. LÄS MER

  7. 25. Harnessing T cell immunity for the prevention and treatment of liver cancer

    Författare :Panagiota Maravelia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hepatocellular carcinoma (HCC) accounts for more than 80% of all diagnosed cases of liver cancer which is a major cause of cancer related fatalities worldwide. With few improvements in the survival rates during the last decades, prevention of HCC is key in reducing its burden globally. LÄS MER