Sökning: "treatment interruption"

Visar resultat 21 - 25 av 32 avhandlingar innehållade orden treatment interruption.

  1. 21. HMBG1 and other soluble factors in HIV-1 pathogenesis

    Författare :Babilonia Barqasho; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; PHI; cytokines; chemokines; immune activation; HMGB1; cell death;

    Sammanfattning : The innate immune system is the first defense mechanism invading pathogens encounter. Macrophages, dendritic cells and cytokines/chemokines are important factors for the functionality of the innate immunity, and provide the adaptive immune system with sufficient signals for the proper action. LÄS MER

  3. 22. Deciphering HIV genetic variability and evolution by massive parallel pyrosequencing and bioinformatics

    Författare :Johanna Brodin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : HIV-1 is a virus with a very variable genome and therefore has the ability to adapt to new environments which include escape from immune pressure and suboptimal antiretroviral treatment. Next-generation sequencing (NGS), especially ultra-deep pyrosequencing (UDPS), has enabled in-depth sequencing studies with a previously unattainable resolution. LÄS MER

  4. 23. Bile acid metabolism in humans : regulation of synthesis and circadian rhythms

    Författare :Amani Al-Khaifi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Interfering with bile acids (BAs) signaling within the enterohepatic circulation (EHC) has recently emerged as an important way of controlling human metabolic homeostasis. This is highly relevant to a number of frequent disease entities such as dyslipidemia, fatty liver disease, insulin resistance, obesity, type 2 diabetes, gallstone disease and BA-induced diarrhea. LÄS MER

  5. 24. Dental behaviour management problems among children and adolescents – a matter of understanding? Studies on dental fear, personal characteristics and psychosocial concomitants

    Författare :Annika Gustafsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dental fear; child; adolescents; dental behaviour management problems; dental attendance; anxiety; psychosocial concomitants;

    Sammanfattning : Dental behaviour management problems among children and adolescents – a matter of understanding? Studies on dental fear, personal characteristics and psychosocial concomitants. Annika Gustafsson, Department of Pedodontics, Institute of Odontology at Sahlgrenska Academy at Göteborg University, Göteborg, Sweden, 2010 The primary aim of this thesis was to study dental fear, personal characteristics and psychosocial concomitants in relation to dental behaviour management problems (DBMP) and dental attendance. LÄS MER

  7. 25. Production simulation as a management tool

    Författare :Torbjörn Ilar; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Produktionsutveckling; Manufacturing Systems Engineering;

    Sammanfattning : This thesis focuses on process simulation and modelling in the context of production engineering. The thesis is presented in the form of seven papers which range in content from the holistic analysis of the application of modelling (papers 1-5) to a detailed examination of some of the areas of weaknesses in commercially available software (papers 6 and 7). LÄS MER