Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Pursuing the fever trail : pathogenesis of blood-stage P. falciparum malaria and pregnancy

   Författare :Niloofar Rasti; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Plasmodium falciparum; malaria; erythrocytes; pregnancy; Uganda; placental sequestration; cytoadhesion; PfEMP1; var2csa; antigenic variation; live-cell proteomic.;

   Sammanfattning : The burden of the most virulent form of human malarias, Plasmodium falciparum, is concentrated among young children and pregnant women in sub-Saharan Africa. Excessive sequestration of parasite-infected red blood cells (pRBCs) in the capillary beds of different organs is the hallmark of P. LÄS MER

3. 2. Immunoglobulins in the adhesion of Plasmodium falciparum-infected erythrocytes in malaria

   Författare :Carin Scholander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Plasmodium falciparum; rosetting; cytoodhesion; immunoglobulins; serum proteins; fibrillar structures; malarial anaemia; placental malaria; PfEMP1;

   Sammanfattning : Characterisation of the delicate cell-to-cell interactions involved in the binding of Plasmodium falciparum- infected erythrocytes to host cells is central for the understanding of the development of severe malaria. Infected erythrocytes adhere in the deep vasculature of several organs, sequestration, leading to cerebral malaria, pulmonary oedema or renal failure. LÄS MER