Sökning: "genomic typing"

Visar resultat 16 - 20 av 20 avhandlingar innehållade orden genomic typing.

  1. 16. Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens

    Författare :Linn Stenfelt; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood Group; P1 antigen; Sda antigen; A4GALT; B3GALNT2; glycosyltransferase; red blood cell; transfusion medicine;

    Sammanfattning : Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. LÄS MER

  3. 17. Genotypic and phenotypic characterisation of Neisseria gonorrhoeae

    Författare :Magnus Unemo; Bengt Wretlind; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The bacterium Neisseria gonorrhoeae (the gonococcus) is the aetiological agent of gonorrhoea, which remains a major sexually transmitted infection/disease (STI/STD) worldwide. The incidence of gonorrhoea was previously high in many countries, Sweden included. The incidence in Sweden culminated in 1970 with 487 cases per 100,000 inhabitants. LÄS MER

  4. 18. Candidate gene analyses and genome-wide screens in multiple sclerosis

    Författare :Vilmantas Giedraitis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Specific disease causing mutations have been identified for many disorders. Most of these disorders are of Mendelian origin and there have been very few successful attempts in the genetic dissection of complex traits. LÄS MER

  5. 19. Adenocarcinoma of the cervix uteri : methods to improve diagnostics : biological markers and HPV testing

    Författare :Susanne Friederike Müller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cervical adenocarcinoma (ADC) represents about 20% of invasive cervical cancers. Implementation of screening programs that have led to a decrease in squamous cell carcinoma (SCC) has only had a limited preventive effect on adenocarcinoma as the incidence of ADC, especially among younger women, has steadily increased in recent decades. LÄS MER

  7. 20. Polyneuropathy associated with monoclonal gammopathy : A clinical, neurophysiological and immunological study

    Författare :Magnus Vrethem; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : This thesis is based upon clinical, neurophysiological, and immunological studies of polyneuropathy (symmetrical impairment of sensory and motor nerve function) in patients with monoclonal gammopathies, that is, patients characterized by proliferation of a plasma-cell clone secreting homogeneous immWloglobulins (M-component), which in some patients has serum antibody reactivity against peripheral nerve myelin.The prevalence of clinical polyneuropathy in patients with monoclonal gammopathy (n=3) was 36%, and the prevalence of all forms of polyneuropathy including patients with neurophysiological signs only andpatients with probable polyneuropathy (signs but no symptoms) was 58%. LÄS MER