Sökning: "chronic lymphocytic leukemia"

Visar resultat 26 - 30 av 85 avhandlingar innehållade orden chronic lymphocytic leukemia.

  1. 26. Molecular genetic studies on Chronic Lymphocytic Leukemia and Acute Myeloid Leukemia - with focus on prognostic markers

    Författare :Kerstin Willander; Peter Söderkvist; Mats Linderholm; Kourosh Lotfi; Sören Lehmann; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The present thesis is focused on the prognostic value of genetic variations and alterations in the initiation and development of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML) patients. Several prognostic markers based on genetic or chromosomal aberrations are today used in clinic in these heterogeneous diseases. LÄS MER

  3. 27. Towards new therapeutic targets : identification of novel tumor markers in chronic lymphocytic leukemia

    Författare :Eva Mikaelsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic Lymphocytic Leukemia (CLL) is the most common leukemia in the Western world and is caused by an abnormal accumulation of B lymphocytes in peripheral blood, bone marrow and lymphoid organs. It is a disease mainly of adults. The clinical outcome of CLL may differ significantly. LÄS MER

  4. 28. ROR1 : a novel receptor tyrosine kinase with unique therapeutic potentials in chronic lymphocytic leukemia

    Författare :Amir Hossein Daneshmanesh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of small B lymphocytes in blood, bone marrow, lymph nodes and other lymphoid tissues. CLL is the most common leukemia in the Western world. Despite significant advances in understanding the pathogenesis, CLL is still a disease with no available cure. LÄS MER

  5. 29. Immunological and molecular studies for the development of vaccine therapy for chronic lymphocytic leukemia

    Författare :Marzia Palma; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic lymphocytic leukaemia (CLL) is a malignant lymphoproliferative disorder which typically affects elderly people. It is the commonest leukemia in the Western adults, accounting for 25-30% of all leukemias and for 10% of all hematological neoplasms. LÄS MER

  7. 30. Molecular and Genetic Evidence for Antigen Selection in the Pathogenesis of Chronic Lymphocytic Leukemia

    Författare :Lesley Ann Sutton; Richard Rosenquist; John Gribben; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGHV4-34; microenvironment; stereotypy; immunoglobulin; intraclonal diversification; clonal evolution;

    Sammanfattning : Antigens play a critical role in the development of chronic lymphocytic leukemia (CLL) by binding to and stimulating leukemic precursor cells at some point during CLL ontogeny. Nevertheless, much remains unknown and further studies are necessary before an accurate model of antigen-drive can be ascertained. LÄS MER