Sökning: "biologically effective dose"

Visar resultat 6 - 10 av 10 avhandlingar innehållade orden biologically effective dose.

  1. 6. In vivo dosimetry of some important industrial chemicals by measurement of their reaction products with hemoglobin

    Författare :Hermes Licea Pérez; Åke Bergman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Sammanfattning : Hemoglobin adduct measurements provide a useful tool for the development of models for risk assessment of chemicals. The measurements can be used to identify reactive metabolites and to determine the in vivo doses of these metabolites. LÄS MER

  3. 7. Experimental Studies of Ursolic Acid and Alkaline Sphingomyelinase in Colon Cancer and Colitis

    Författare :David Andersson; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Sphingomyelin (SM) is a sphingolipid present in all eukaryotic cell membranes. Hydrolysis of SM by sphingomyelinase (SMase) generates ceramide, which has effects on cell-cycle regulation and apoptosis. LÄS MER

  4. 8. Tumor radiosensitivity and proliferation as parameters for optimizing radiotherapy

    Författare :Mattias Hedman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Radiotherapy is a widely used method to treat malignant tumors. However, the sensitivity to the treatment varies between tumors, and local tumor control is not always achieved. The balance between treatment success and the side effects of the treatment affords important information for developing treatment schedules at patient population level. LÄS MER

  5. 9. Periodontal implications of Salvadora persica L

    Författare :Reham A Al-Babtain; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Periodontal disease is a major public health problem throughout the world and is the most common cause of tooth loss in adults. For periodontitis to develop, specific gram-negative, anaerobic bacteria must predominate in the subgingival microflora, but simple the presence of these bacteria is insufficient to cause periodontal disease as disease progression involves a complex, sequential relationship between infection, inflammation and tissue destruction. LÄS MER

  7. 10. Cellular Effects of Cystatins

    Författare :Samar Hunaiti; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystatin C; Cystatin D; Galectin-1; Puncta assay; HoloMonitor; Cancer cells; Apoptosis; Cathepsin C;

    Sammanfattning : The exact cellular functions of cystatins are still unknown, and the molecular mechanism leading to their internalization into cells is not yet fully understood. Commonly the cystatins are known to inhibit human lysosomal cysteine proteases (cysteine cathepsins) and it is supposed that this is their primary physiological role. LÄS MER