Sökning: "acinar cells"

Visar resultat 11 - 15 av 28 avhandlingar innehållade orden acinar cells.

  1. 11. Chronic pancreatitis fibrogenesis : the role of TGFB pathway inhibitor Smad7 in the fibrosis development

    Författare :Xuan Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic pancreatitis is characterized by progressive inflammation, acinar atrophy and fibrosis. Transforming growth factor-B signaling (TGFB) is the most potent fibrogenic cytokine known, and its increased expression is a common denominator for fibrosis in chronic pancreatitis. LÄS MER

  3. 12. Long-term effects of cholecystokinin on exocrine and endocrine pancreas

    Författare :Thomas Gasslander; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The gastrointestinal hormone cholecystokinin (CCK) is known to be oneof the most potent stimulators of pancreatic growth. CCK is alsosuggested to be an initiator and/or promotor of pancreatic carcinogenesis. LÄS MER

  4. 13. Oral chronic Graft-versus-host disease : clinical and pathological staging

    Författare :Victor Tollemar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allogenic hematopoietic cell transplantation (HCT) is a curative treatment for many patients with immune- hematopoietic disorders, mainly hematopoietic cancers as leukaemia. Chronic Graft-versus-Host Disease (cGVHD) is a major long-term complication, associated with mortality and morbidity following allogenic HCT. LÄS MER

  5. 14. The role of endogenous hypercholecystokininemia and hypergastrinemia in growth and carcinogenesis of the exocrine pancreas

    Författare :Ming Chu; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The gut hormones cholecystokinin (CCK) and gastrin are phylogeneticallyand structurally related. Under normal conditions, CCK regulates growth of the exocrine pancreas and gastrin growth of the oxyntic mucosa of the stomach. LÄS MER

  7. 15. Regulation of Hedgehog signalling during development and carcinogenesis

    Författare :Marie Fiaschi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hedgehog (Hh) signalling is one of the most important signalling networks in the body and, when miss-regulated, has been implicated in many human tumours, particularly that of skin (Basal Cell Carcinoma, BCC) and brain (medulloblastoma). BCC most commonly arises due to mutations in the gene sequence of the Hh receptor protein PATCHED1 (PTCH1). LÄS MER