Sökning: "Rotavirus"

Visar resultat 16 - 20 av 41 avhandlingar innehållade ordet Rotavirus.

  1. 16. Host susceptibility to rotavirus infection and development of antibody-based immunotherapy

    Författare :Gökçe Günaydın; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotavirus infects mature enterocytes of the small intestine of young children and cause gastroenteritis, leading to approximately 500 000 deaths annually worldwide, 85 % of which occur in the developing world. The main objectives of the thesis were to investigate host genetic factors leading to differential susceptibility to rotavirus infections and to develop an antibody-based oral therapy against the infections. LÄS MER

  3. 17. Immune responses related to protection against rotavirus after natural infection and vaccination

    Författare :Kari Johansen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotavirus is the most important cause of severe gastroenteritis in children under five years of age and is estimated to be responsible for one-third of all diarrhea-associated hospitalizations and 600,000 deaths/ year worldwide. 1500-1700 rotavirus-associated hospitalizations of children are estimated to occur annually in Sweden (3. LÄS MER

  4. 18. Acute gastroenteritis in children : a study with special emphasis on enteric adenovirus and rotavirus infections

    Författare :Ingrid Uhnoo; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 19. The introduction of rotavirus vaccine in Sweden : setting the scene and short term outcomes

    Författare :Lina Schollin Ask; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: The rotavirus causes the most severe cases of viral gastroenteritis in small children worldwide, resulting in both high morbidity and mortality. The World Health Organization has recommended vaccination against the rotavirus since 2009 and the vaccine had been introduced by more than 90 countries in 2017. LÄS MER

  7. 20. Passive immunisation as therapy for gastrointestinal infections in children

    Författare :Thomas Casswall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Passive immunisation; treatment; bovine antibodies; chicken antibodies; rotavirus; Escherichia coli; ETEC; EPEC; Helicobacter pylori; clinical trials; infants; children;

    Sammanfattning : Several prophylactic studies in animals and humans have shown potential efficacy of oral therapy with non-human antibodies against different pathogens. Passive immunisation with oral antibodies against different pathogens is an attractive way to treat different gastrointestinal infections caused by pathogens such as rotavirus or enteropathogenic and enterotoxigenic Escherichia coli (EPEC; ETEC). LÄS MER