Sökning: "Irs1"

Visar resultat 16 - 17 av 17 avhandlingar innehållade ordet Irs1.

1. 16. Expression of inflammatory and insulin signaling genes in acute and chronic stress

   Författare :Anna Witasp; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The acute surgical stress response induces a short-term inflammatory and insulin resistant condition, commonly producing hyperglycemia, which is strongly associated to morbidity and mortality in postsurgical patients. The chronic state of renal insufficiency, on the other hand, represents a long-term stress associated with alarmingly high mortality rates, primarily due to cardiovascular complications, and is similarly related to chronic inflammation, oxidative stress, and insulin resistance. LÄS MER

3. 17. Genetic and immunological risk factors of gestational diabetes mellitus

   Författare :Nael Shaat; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GDM; Association; genetics; gestational diabetes mellitus metabolic syndrome; MODY; type 1 diabetes; risk factors; type 2 diabetes; Endocrinology; diabetology; secreting systems; autoimmunity; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : Gestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. LÄS MER