Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells

   Författare :Sara Pijuan Galitó; Cecilia Annerén; Lena Kjellén; Christopher Ward; Uppsala universitet; []
   Nyckelord :Pluripotent stem cells; Inter-alpha inhibitor; culture method; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

   Sammanfattning : Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while maintaining their capacity to differentiate into any cell type of an organism, thus offering novel sources for drug screening, in vitro disease modelling, and cell replacement therapies. However, due to their sensitive nature, many PSC lines are still cultured using undefined components such as serum or serum-derived components, on either feeder cells or complex protein mixes such as Matrigel or gelatine. LÄS MER

3. 2. Novel biomarkers in regulating human dense connective tissue repair

   Författare :Junyu Chen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Painful and degenerative disorders of the musculoskeletal system pose a tremendous burden on the healthcare system. One main reason is the limited knowledge of the underlying key factors and pathways responsible for the suboptimal and often varying healing outcomes of dense connective tissues (CTs), such as tendons, ligaments and knee meniscus, which have vital supportive, protective and force transmitting roles in the human body. LÄS MER