Sökning: "Heparin-binding protein HBP"
Visar resultat 11 - 15 av 18 avhandlingar innehållade orden Heparin-binding protein HBP.
11. Neutrophil granule proteins : modulators of the immune response
Sammanfattning : Polymorphonuclear leukocytes (PMN) are multifunctional cells of the innate immune system which represent the advance guard in inflammatory reactions. Via the release of granule proteins the PMN communicates with the endothelium, monocytes, dendritic cells, and lymphocytes and is thereby critically involved in the fine tuning of the host defense system. LÄS MER
12. Clinical and pathophysiological aspects of sepsis
Sammanfattning : Severe sepsis and septic shock represent challenging problems for the health care system. Despite adequate antibiotics and modern intensive care, severe sepsis is associated with a substantial mortality rate of around 30%, which rises even higher if exacerbated by septic shock, and the incidence continues to increase. LÄS MER
13. Vascular effects of endothelin in experimental lung injury
Sammanfattning : Acute lung injury remains a frequent and life threatening consequence of severe sepsis. This thesis has investigated the role of the endothelin (ET) system in sepsis-induced lung injury, with special reference to its effects on two hallmarks of this syndrome - formation of edema and pulmonary hypertension. LÄS MER
14. Post-cardiac arrest care. Targeted temperature management and coronary care
Sammanfattning : AbstractOut-of-hospital cardiac arrest is a devastating manifestation of coronary artery disease. For patients who are initially resuscitated and are admitted to an intensive care unit, mortality is high. Roughly half of all patients die, primarily due to neurological injury. LÄS MER
15. Phagocytic cells and Streptococcus pyogenes in invasive infections : an inflammatory relationship
Sammanfattning : Severe Streptococcus pyogenes infections, such as streptococcal toxic shock syndrome and necrotizing soft tissue infections, are rare but life threatening conditions. They are characterized by high bacterial load and a hyper-inflammatory state. The aim of this thesis was to investigate interactions between S. LÄS MER