Sökning: "GAD65 epitopeC-peptide"

Hittade 1 avhandling innehållade orden GAD65 epitopeC-peptide.

1. 1. The importance of immunological, genetic and clinical factors for beta cell function in childhood diabetes

   Författare :Eva Örtqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Type I diabetes; HLA-DQ; GAD65Ab; 1A-2Ab; ICA; GAD65 epitopeC-peptide; clinical remission; beta cell rest; diazoxide.;

   Sammanfattning : Type I diabetes is caused by environmentally initiated, progressive autoimmune destruction of pancreatic beta cells in genetically susceptible individuals, which results in insulin deficiency and hyperglycemia. At diagnosis, about 10-20 % of beta cells remain, but after insulin therapy is started, a period with regained secretive capacity follows. LÄS MER