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1. 1. The nuclear factor k[kappa]B signal transduction pathway : its role in atherogenesis and intimal hyperplasia

   Författare :De-xiu Bu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Atherosclerosis; intimal hyperplasia; NF-kappaB; NGAL; Telomerase; Leukotriene B4;

   Sammanfattning : Vascular inflammation is a hallmark of major cardiovascular diseases such as atherosclerosis, and also suggested as a critical component implicated in intimal hyperplasia. Given its central role in regulating expression of inflammatory genes, the nuclear factor kappaB (NF-kappaB) signal transduction pathway was postulated to play an important role in these pathological processes. LÄS MER